IGF-1 LR3 (Receptor Grade) 1mg
IGF-1 LR3 for sale is available in lyophilized powder form, in 1mg vials.
What is IGF1-LR3?
LR3-IGF-I, Human (Receptor Grade) is a Human Recombinant, single, non-glycosylated, polypeptide chain containing 83 amino acids. It is an analog of human IGF-1 comprising the complete human IGF-1 sequence with the substitution of an Arginine (Arg or R) for the Glutamic Acid (Glu or E) at position 3 (hence R3), and a 13 amino acid extension peptide at the N-terminus.
- IGF1 LR3 is an analogue of human IGF-1 that has been modified to include a 13 amino acid N-terminus extension and the substitution of Arginine for Glutamic Acid at position 3.
- As a result of these modifications, IGF-1 LR3 is approximately three times more potent than IGF-1 and possesses an increased half-life due to lowered affinity for binding to the Insulin-Like Growth Factor Binding Proteins (IGFBPs).
- IGFLR3 retains the ability to bind agonistically to the IGF–1 receptor with improved metabolic stability, relative to IGF–1.
- The supplementation of mammalian cell cultures with Long R3 IGF1 at a much lower concentration results in more highly elevated productivity than with standard concentrations of insulin and/or standard IGF1.
- IGF-LR3 is able to stimulate the type 1 IGF receptor and thus induce a higher level of activation of intracellular signaling , which is responsible for promoting cell proliferation and the inhibition of apoptosis .
This analog has been engineered with the express purpose of increasing biological activity. IGF-1 Long[R3] is significantly more potent than IGF-1 in vitro and in vivo. The enhanced potency is due to the markedly decreased binding of IGF-1 Long[R3] to all IGF binding proteins. These binding proteins normally inhibit the biological actions of IGFs.
IGF-1 stands for insulin-like growth factor. It is a natural substance that is produced and is at its highest natural levels during puberty. During puberty IGF-1 is the most responsible for the natural muscle growth that occurs during these few years.
Common benefits of IGF-1 LR3 include:
increased amino acid transport to cells
increased glucose transport
increased protein synthesis
decreased protein degradation
increased RNA synthesis
Buy IGF 1 LR3 online from GenX Peptides.
We offer the highest grade and purity of IGF1 LR3 for sale at a competitive price in the USA. For best results buy IGF-1 LR3 of the highest quality from GenX Peptides.
For more information on IGF-1 LR3 peptide please visit Pubmed.
MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK
PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA
Lyophilized recombinant human Long R³ Insulin-like Growth Factor-1 (rhLR³ IGF-1) is stable at room temperature for 90 days. However, it should be stored in a freezer below -8C for any extended period of time
For Research Only. Not Intended for Diagnostic or Therapeutic Use
Products on the website are not intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease and are not intended to affect the structure or any function of the body. The use of our products are for only research/laboratory purposes.
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