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HCG

$49.99

Human Chorionic Gonadotropin HCG for sale 5000iu

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Description

About HCG: HCG stimulates the natural testosterone production system of low levels of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH).

Human chorionic gonadotropin (hCG) is glycoprotein hormone secreted during pregnancy that has important roles in the maintenance of pregnancy.1,2 It exists as a heterodimer that is composed of two subunits, hCGα and hCGβ, that are subject to glycosylation, generating a variety of glycosylated hCG variants that have distinct biological functions.3,4 The expression of genes encoding hCGα and hCGβ are regulated by a variety of hormones, growth factors, and cytokines.4 It is secreted by placental trophoblasts during early pregnancy and serum hCG levels peak from gestational weeks 7 to 10.1 hCG has numerous roles in pregnancy, including stimulating production of progesterone from the corpus luteum and promoting angiogenesis of uterine vasculature and the growth of fetal organs.5

hCG can be used for ELISA, immunohistochemistry (IHC), and Western blot (WB) applications.

References & Product Citations

Product Description References

1. Stenman, U.-H., Alfthan, H., and Hotakainen, K. Human chorionic gonadotropin in cancer. Clin. Biochem. 37(7), 549-561 (2004).

2. Gadkari, R.A., Roy, S., Rekha, N., et al. Identification of a heterodimer-specific epitope present in human chorionic gonadotrophin (hCG) using a monoclonal antibody that can distinguish between hCG and human LH. J. Mol. Endocrinol. 34(3), 879-887 (2005).

3. Cole, L.A. HCG variants, the growth factors which drive human malignancies. Am. J. Cancer Res. 2(1), 22-35 (2012).

4. Nwabuobi, C., Arlier, S., Schatz, F., et al. hCG: Biological functions and clinical applications. Int. J. Mol. Sci. 18(10), 2037 (2017).

5. Cole, L.A. Biological functions of hCG and hCG-related molecules. Reprod. Biol. Endocrinol. 8, 102 (2010).

Technical Information

Unit Size 5000iu
Unit Quantity 1 Vial
Appearance White Powder
Applications ELISA, IHC, WB
Synonyms Human Chorionic Gonadotropin
Immunogen Native hCG protein purified from human urine
Storage -20°C
Stability ≥ 1 year

Additional information

Weight 1 oz
Dimensions 1 × 1 × 1 in