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Dermorphin 5mg


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Dermorphin Product Description

Dermorphin is an opioid peptide originally isolated from the skin of South American frogs (Ph. sauvagei).1 It binds to μ-opioid receptors (Ki = 0.54 nM) and is selective for μ- over δ-opioid receptors in radioligand binding assays (Ki = 929 nM). In vivo, dermorphin (1.9 µmol/kg, i.p.) inhibits noxious stimuli-induced neuronal firing in the nucleus lateralis anterior and ventrobasal complex in rats.2 It inhibits the electrical stimulation-induced C fiber response in rat dorsal horn nociceptive neurons. Dermorphin (10-120 pmol/animal, i.c.v.) delays gastric emptying, inhibits gastric acid secretion, and slows colonic motility in pylorus-ligated rats.

References & Product Citations

Product Description References

1. Usenko, A.B., Emel’yanova, T.G., and MIasoedov, N.F. Dermorphins are natural opioids with an unique primary structure that determines their biological specificity. Biol. Bull. Russ. Acad. Sci. 29, 154-164 (2002).

2. Melchiorri, P., and Negri, L. The dermorphin peptide family. Gen. Pharmacol. 27(7), 1099-1107 (1996).

Dermorphin Peptide Technical Specifications

Unit Size


Unit Quantity

1 vial

Molecular Formula


Molecular Weight

802.9 g/mol




lyophilized powder

Peptide Purity



Chemical Synthesis


Lyophilized Dermorphin Peptide is stable at room temperature for 90 days. However, it should be stored in a freezer below -8C for any extended period of time

Safety Information

For Research Only. Not Intended for Diagnostic or Therapeutic Use

Additional information

Weight1 oz
Dimensions1 × 1 × 2 in


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Dermorphin 5mg Peptide Vial For Sale
Dermorphin 5mg