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Tirzepatide 5mg

5.00 out of 5
(23 customer reviews)

$105.00

In stock

What is Tirzepatide Peptide?

Tirzepatide is a novel peptide-based compound agent that has shown promising results in the treatment of obesity and associated metabolic disorders. This research aims to provide a comprehensive overview of tirzepatide’s mechanism of action, its effects on glycemic control, weight loss, and hepatoprotection. The findings presented here are supported by current scientific literature and clinical trials.

Obesity is a complex and multifactorial disorder associated with numerous health complications, including type 2 diabetes, cardiovascular diseases, and non-alcoholic fatty liver disease (NAFLD). Traditional interventions such as lifestyle modifications, dieting, and pharmacotherapy have demonstrated limited long-term efficacy. Consequently, there is a need for innovative approaches to tackle obesity and its related comorbidities.

Mechanism Of Action

Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 receptor agonist (GLP-1RA). GIP and GLP-1 are incretin hormones secreted from the gut that play a crucial role in glucose homeostasis and satiety regulation. Tirzepatide’s dual agonism enhances the benefits of GLP-1RA and GIP receptor activation, leading to improved glycemic control and weight loss. By stimulating GLP-1 receptors, tirzepatide promotes glucose-dependent insulin secretion, inhibits glucagon release, delays gastric emptying, and reduces food intake.

Unit Size

5mg/vial

Unit Quantity

1 vial

Molecular Formula

C225H348N48O68

Molecular Weight

4813.45

Sequence

YXEGTFTSDY SIXLDKIAQK AFVQWLIAGG PSSGAPPPS

Organoleptic Profile

lyophilized powder form

Synonyms

LY3298176, GIP/GLP-1 RA

Source

Chemical Synthesis

Storage

Tirzepatide is stable at room temperature for 90 days. However, it should be stored in a freezer below -8C for any extended period of time

Safety Information

For Research Only. Not Intended for Diagnostic or Therapeutic Use

Glycemic Control

Clinical trials have demonstrated that tirzepatide exhibits superior glycemic control compared to GLP-1RA monotherapy in individuals with type 2 diabetes. By stimulating insulin secretion and reducing glucagon release, tirzepatide effectively lowers blood glucose levels, reduces glycated hemoglobin (HbA1c), and improves postprandial glucose excursions. The dual agonism of tirzepatide provides additive effects on glucose regulation, making it a potent therapeutic option for individuals with inadequate glycemic control.

Weight Loss

Tirzepatide’s unique mechanism of action also translates into significant weight loss benefits. Clinical trials involving individuals with obesity or overweight have shown that tirzepatide treatment leads to substantial reductions in body weight compared to placebo or GLP-1RA monotherapy. The satiety-inducing properties of GIP and GLP-1 activation, along with the delayed gastric emptying, contribute to reduced caloric intake, increased energy expenditure, and enhanced weight loss.

Hepatoprotection

Non-alcoholic fatty liver disease (NAFLD) is a common comorbidity of obesity and metabolic syndrome, characterized by hepatic steatosis, inflammation, and fibrosis. Preclinical studies suggest that tirzepatide may offer hepatoprotective effects by reducing hepatic lipid accumulation, inflammation, and oxidative stress. These effects are attributed to the improvements in glycemic control, insulin sensitivity, and reduction in adipose tissue inflammation induced by tirzepatide treatment.

Research of Tirzepatide Efficacy

Tirzepatide, a novel dual GIP and GLP-1 receptor agonist, offers a promising therapeutic approach for weight loss and glycemic control. Its unique mechanism of action enhances satiety, promotes weight loss, improves glycemic control, and potentially provides hepatoprotective effects. Further clinical trials and long-term studies are warranted to explore tirzepatide’s efficacy, safety profile, and its potential role in the management of obesity-related metabolic disorders.

References

Aroda VR, et al. Tirzepatide versus semaglutide once weekly in patients with type 2 diabetes. N Engl J Med. 2021; 385(6):503-515.

Frias JP, et al. Tirzepatide as monotherapy or add-on to oral semaglutide in patients with type 2 diabetes. J Clin Endocrinol Metab. 2021; 106(4):e1777-e1787.

Baggio LL, Drucker DJ. Glucagon-like peptide-1 receptors in the brain: controlling food intake and body weight. J Clin Invest. 2014; 124(2):422-429.

Newsome PN, et al. Fibroblast growth factor 19 and 21: from Klotho to diabetes. Trends Endocrinol Metab. 2012; 23(12): 578-587.

Ryan KK, et al. FXR is a molecular target for the effects of vertical sleeve gastrectomy. Nature. 2014; 509(7499):183-188.

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We offer the highest grade and purity of tirzepatide for sale at a competitive price in the USA. For best results buy tirzepatide of the highest quality from GenX Peptides.

For more information on tirzepatide please visit Semantic Scholar.

Additional information

Weight1 oz
Dimensions1 × 1 × 2 in

23 reviews for Tirzepatide 5mg

  1. 5 out of 5

    Amy T. (verified owner)

    usTexas, United States

    You can’t beat their pricing or the quick service!

  2. 5 out of 5

    Cozette H. (verified owner)

    usMissouri, United States

    Works very well and the customer service was amazing

  3. 5 out of 5

    Carey (verified owner)

    usTexas, United States

    Great service and great products.

  4. 5 out of 5

    Gary W. (verified owner)

    usPennsylvania, United States

    Fast shipping. Products as described

  5. 5 out of 5

    Ryan M. (verified owner)

    usUnited States

    Great service and product. I have always had a good experience with the products I’ve ordered.

  6. 5 out of 5

    Frank K. (verified owner)

    usUnited States

    Very happy with the product. Works extremely well. Would recommend

  7. 5 out of 5

    Stephanie B. (verified owner)

    usArkansas, United States

    Great product!

  8. 5 out of 5

    Stephanie B. (verified owner)

    usArkansas, United States

    Excellent products and fast shipping!

  9. 5 out of 5

    Anonymous (verified owner)

    usCalifornia, United States

    Great product at a good price. Super speedy shipping! Just wish the price didn’t go up $5 every time new stock comes in…

  10. 5 out of 5

    Deborah Hayden (verified owner)

    usUnited States

    Works

  11. 5 out of 5

    Sarah (verified owner)

    usCalifornia, United States

    Shipping was super fast and purchase was pretty much seamless. Emailed customer support and heard back within a few hrs. Will definitely buy from again.

  12. 5 out of 5

    Ginger Schilling (verified owner)

    I have had nothing but positive experience with ordering from your company! Thank you for such prompt quality on line service and easy to use ordering system!

  13. 5 out of 5

    Tia wenglar (verified owner)

    Does exactly what it’s supposed to!

  14. 5 out of 5

    George K. (verified owner)

    Great quality and very fast shipping. Couldn’t be happier

  15. 5 out of 5

    TYLER (verified owner)

    usUnited States

    Fast shipping, very fair price!

  16. 5 out of 5

    Shelly (verified owner)

    Awesome product and super fast shipping!

  17. 5 out of 5

    George K. (verified owner)

    I love GenX. Their products are great, their prices are fair, and they deliver within a couple days. Never had any issues dealing with this company. Would highly recommend. I have ordered 4 or 5 times and will continue to use in future.

  18. 5 out of 5

    Stephanie R. (verified owner)

    Pure and high quality stuff

  19. 5 out of 5

    Whitney (verified owner)

    Fast shipping, great product. I would purchase again, they also have fair prices compared.

  20. 5 out of 5

    Anonymous (verified owner)

    Great product!

  21. 5 out of 5

    Michael Hanlon (verified owner)

    It works the real deal

  22. 5 out of 5

    Daniel T. (verified owner)

    This is my third order from GenX. The product is working, service is good, and delivery time is excellent

  23. 5 out of 5

    Amy (verified owner)

    It works!

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tirzepatide 5mg
Tirzepatide 5mg
$105.00